Expression, antibody-based methods, etc.). Within the main types of biotechnological drugs, we can mention: monoclonal antibodies, recombinant proteins, vaccines or advanced therapies. Compared to the manufacturing of chemical drugs, the process of developing a biotech drug is much longer and more expensive. In this sense, from the discovery and development of a molecule, until the final drug is marketed, more than 15 years of research may pass. This is due to a greater demand for the specific requirements for their evaluation and control of these drugs, due to their peculiarities and the type of technology used in their manufacture.
Manufacturing process of biotechnological drugs. For the production of biotechnological drugs, the starting point is a homogeneous material made up of microorganisms (viruses, bacteria or yeasts) or an animal cell line (such as mouse myeloma or chinese hamster e commerce photo editing service ovary cells) genetically modified to obtain the biotherapeutic protein of interest. . Large-scale cultures of these microorganisms or cell lines are then obtained. The recombinant protein is isolated and purified, inactivation or elimination of possible contaminating viruses, and it is packaged in a sterile way to obtain the final product in the form of a solution or lyophilized. Thus, the biotechnological drug production process basically follows four well-differentiated stages: 1) production of the original
cell line that contains the gene that allows the desired protein to be manufactured. 2) culture of large numbers of cells that produce the protein. 3) isolation and purification of the protein. 4) preparation of biological treatment for use in patients. Biotechnology as a therapeutic strategy in cancer as a result of numerous research studies, it has been proven that the production of biotechnological medicines offers a wider range of possibilities to treat cancer . In this sense, one of the greatest advances in cancer treatment lies in the possibility of establishing